49ers Reportedly Suffer Big Loss Ahead Of Kickoff Thursday Night

In Sunday's victory over the Los Angeles Rams, wide receiver Brandon Aiyuk of the San Francisco 49ers was injured.

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For the past several days, Aiyuk's participation in tonight's game, which comes on short rest, has been in doubt.

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Former first-round selection "not expected to play" against the New York Giants on Thursday Night Football, according to ESPN's Adam.

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Even more telling of Aiyuk's absence is that San Francisco activated veteran wide receiver Chris Conley off the practice squad in advance of tonight's game.

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49ers quarterback Brock Purdy favors Aiyuk, who reached 1,000 yards receiving in 2022 for the first time.

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San Francisco will miss standout running back Saquon Barkley, starting offensive lineman Andrew Thomas and Ben Bredeson, and third-year pass rusher Azeez Ojulari while Aiyuk is out.

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